Featured News More
Support our research on CMT
Ohio State University has established a Charcot-Marie-Tooth Disease Type 2E Research Fund to support research on the mechanisms and treatment of Charcot-Marie-Tooth disease caused by mutations in neurofilament protein L
MBoC Research Highlights webinar
Our paper on Regulation of neurofilament length and transport by a dynamic cycle of phospho-dependent polymer severing and annealing is one of three papers selected for a talk in the ASCB’s Research Highlights Webinar to promote Molecular Biology of the Cell’s special issue on Cell Biology of the Nervous System
ABOUT OUR LAB
We are cell biologists in the Department of Neuroscience at Ohio State University. We study the cytoskeleton of nerve cells and the mechanism of axonal transport.
Our main focus is the biology neurofilaments in health and disease. We use a broad range of cellular and molecular techniques to study the transport and assembly dynamics of neurofilaments in nerve cells.
Our core expertise is in light microscopy, protein biochemistry and nerve cell culture.
Recent Publications More
Nowier RM, Johnson CM, Fenn JD, Brown A & Jung P (2026)
Neurofilament transport kinetics can be explained by the activity of small numbers of independent kinesin and dynein motors
Biophysical Journal, in press
PubMed
Jahan N, York HM, Bailey HM, Swann IC, Leterrier C, Spiliotis ET, Aiken J, Tymanskyj SR, Brown A, Winckler B & Fu MM (2026)
Integrating cytoskeletal systems in neurons and glia: dynamic orchestration of structure and function
Journal of Neuroscience, in press
CONTACT US
Department of Neuroscience
Ohio State University
Rightmire Hall
1060 Carmack Road
Columbus, OH 43210
Office: 614-292-1205
Lab: 614-292-1367
Email: brown.2302@osu.edu